Abstract: The organic integration of professional education and innovation and entrepreneurship education is an important direction for universities to deepen education reform, and is an effective mean to promote the cultivation of innovative talents and build an innovative country. Based on the analysis of the main problems existing in the teaching of the“integration of specialty and innovation and entrepreneurship”course in universities at present, takes the foundation of mechanical manufacturing course as an example, this paper discusses the teaching design ideas and practice paths of the“integration of specialty and innovation and entrepreneurship”course, and puts forward the modularization of professional course knowledge, the refinement of innovation and entrepreneurship projects from modular knowledge, the improvement of the challenge and innovation of projects in the promotion of projects, and the adoption of multi-dimensional evaluation mechanism in the assessment process. At the same time, the practice has proved that in the teaching process of“integration of specialty and innovation and entrepreneurship”course, innovating teaching means, expanding practical links, and actively guiding students'thinking are of great significance to the cultivation of students'innovation and entrepreneurship ability. The thread of teaching design and practical exploration will also provide reference for the reform of other“integration of specialty and innovation and entrepreneurship”courses.

Key words: “Integration of specialty and innovation and entrepreneurship”, Teaching design, Teaching practice, Innovation projects, Challenging learning, Evaluation mechanism