Abstract: The first lesson of innovation and entrepreneurship (referred to as "double entrepreneurship") has a special impact on college students. The use of literature, expert consultation, research and other methods to explore this has positive significance. The research shows that the first lesson of "mass entrepreneurship and innovation" exists: insufficient exploration of ideological and political elements, lack of deep understanding of teachers; vague cognition of students; insufficient integration of multi-disciplinary and professionalism; contradiction between flexible core and rigid requirements, etc. Suggestions: fully explore the ideological and political elements; strengthen the professional training of teachers; pay attention to the first lesson; artistically present multidisciplinary integration and professional integration, etc., to better cultivate innovative college students.

Key words: The first lesson of "innovation and entrepreneurship", Teaching exploration, Reflection