Abstract: Innovation and entrepreneurship education is an important way to improve the quality of talent training. As the foundation of innovation and entrepreneurship education in colleges and universities, the basic course of innovation and entrepreneurship has always been the breakthrough point of teaching reform research. CDIO concept is a new student-centered teaching concept, which is highly compatible with the goal of entrepreneurship and innovation education. By analyzing current situation and problems of innovation entrepreneurship development, expounds the definition of the CDIO and promote double gen education, by means of project driving, the CDIO concept of conception, design, implementation, operation combined with teaching, explores the application of the CDIO concept in double gen foundation course strategy, in order to improve college students' innovative spirit and practical ability to provide the reference.

Key words: CDIO, Innovation and entrepreneurship courses, The application strategy