Abstract: The sudden epidemic of novel coronavirus pneumonia has presented unprecedented challenges to all the work in colleges and universities. With the advent of the post epidemic era, “the ideological and political curriculum” in universities should actively adapt to the new situation, update educational ideas in time, change teaching methods, and take “ideological and political education” as the traction to carry out the reasonable and systematic integration design for various curriculum, in order that a new pattern of "curriculum ideological and political" can be built, and the fundamental task of “establishing morality and cultivating talents” can be implemented. Starting from the necessity of combining the contents of “the integration of Ideological and political education” and “innovation and entrepreneurship curriculum”, on basis of which this paper compares and analyzes their differences before and after the epidemic situation. Taking the course of "innovation and entrepreneurship foundation" as an example, it not only provides the design scheme of “Ideological and political integration”, but through organic integration of Ideological and political education elements, curriculum teaching practice on “innovation and entrepreneurship” and educational theory on “ideological and political” are closely linked, the new pattern of cultivating talents on the basis of seriation and integration is formed as well.

Key words: Post epidemic era, Curriculum ideological and political, Integration design, Innovation and entrepreneurship foundation