Abstract: In the era of precision medicine, medical students from different majors have to adapt to the changes in clinical practice introduced by genomic medicine. Thus, it is required to reform and optimize the traditional teaching content and mode of medical genetics. In accordance with the ideas of clinical application-based orientation, scientific research-driven education, and cultivating innovative talents, the instruction mode for medical genetics can be constructed based on four aspects: optimizing the modular curriculum settings, exploring the innovative teaching methods, strengthening the all-round clinical practice, and renewing the featured multidisciplinary investigations to integrate clinic, education and research in the whole teaching process. The ultimate purpose of the above reform is to cultivate senior medical professionals with systematic knowledge structure and well-trained practical skills who can meet the needs of current development in the precision medicine.

Key words: Medical genetics, Genomics, Precision medicine, Integration of clinic, education and research, Reform of teaching mode, Education of medical students