Abstract: Carrying out innovation and entrepreneurship education and cultivating innovative and entrepreneurial talents to meet the needs of social development is the duty and mission entrusted to colleges and universities by the new era. It is also an important measure to promote university teaching reform and improve the quality of talent training. Innovation and entrepreneurship education is still in the initial stage of exploration, and there are still problems such as incomplete understanding of concepts, incomplete curriculum system, imperfect teaching staff, imperfect operating mechanism and so on.In terms of the problems existing in the development of innovative entrepreneurship education in local colleges and universities, this paper discusses the training path of innovative and entrepreneurial talents in local colleges and universities from four aspects: curriculum system, teaching staff, operation mechanism and mass entrepreneurship and innovation culture, based on the definition and analysis of the concept of OBE, in order to provide new ideas for the cultivation of innovative and entrepreneurial talents in local colleges and universities.

Key words: Innovation and entrepreneurship, OBE, Teaching reform, Talent training