Abstract: At present, college students' innovation and entrepreneurship guidance courses are widely offered in colleges and universities, but the quality of courses offered and student learning effects are uneven. This research analyzes the current situation of innovation and entrepreneurship learning for medical and non-medical students in colleges and universities, discovers the problems in innovation and entrepreneurship curriculum education, and proposes targeted improvement measures to help the development of national innovation and entrepreneurship strategies and help universities improve the effectiveness of innovative talent training provide a theoretical basis.

Key words: Innovation and entrepreneurship, Learning effect, Comparative study