Abstract: The deepening of the integration of production and education, coupled with the "four new" construction of colleges and universities, put forward new requirements for the talent training of application-oriented undergraduate colleges and universities, and gave new connotations to the innovation and entrepreneurship education of application-oriented colleges and universities. In recent years, applied colleges and universities have widely carried out innovation and entrepreneurship education and achieved certain results. However, there are still shortcomings in the top-level design of innovation and entrepreneurship education, system construction, teacher level, curriculum construction and other aspects, which still need to be further improved. Starting from the strategy of rejuvenating the country through science and education, this paper comprehensively analyzes the integration of innovation and entrepreneurship education practice into all aspects of talent training and the whole process of innovative talent training in application-oriented colleges and universities, so as to achieve interdisciplinary integration, interdisciplinary learning and collaboration inside and outside the school, in order to further promote the sustainable and high-quality development of innovation and entrepreneurship education in application-oriented colleges and universities.

Key words: Integration of production and education, “Integration of specialization and innovation”, Application-oriented university, Innovation and entrepreneurship education, Path innovation and practice, Strengthen moral education and cultivate people