Abstract: Colleges and universities are one of the main positions of innovation. Many attempts and explorations have been made on the integration of innovation and entrepreneurship education and professional education, but there are still many problems. It is critical to continuously explore a more scientific and reasonable integration mode between the two. This article will specifically analyze the problems of the integration of innovation and entrepreneurship education and professional education in colleges and universities, and propose a new method based on the "three spirals" theory to integrate innovation and entrepreneurship education with professional education in order to achieve the expected educational goals.

Key words: Triple helix theory, Innovation and entrepreneurship education, Professional education, Curriculum system