Abstract: In order to meet the needs of social development for the cultivation of high-level applied undergraduate talents, it is necessary to comprehensively promote the“specialization and innovation integration”talent cultivation model. In order to realize the deep integration of professional education and innovation and entrepreneurship education, a professional and innovative talent cultivation model based on“establishing, interesting and promoting”have been built around the course system of solid waste treatment and disposal, and have carried out teaching practice for 9 years. The practice includes optimizing the traditional professional curriculum system, consolidating the foundation of professional education, highlighting the“establishing”of talent training mode; Building a new media platform for professional curriculum, enhancing the interest of professional education, highlighting the“interesting”of talent training mode; Creating a new model of innovative and entrepreneurship curriculum, enhancing the height of innovative and entrepreneurship education, highlighting the“promoting”of talent training mode. The exploration of the specialized and innovative talent cultivation mode based on“establishing, interesting and promoting”provides a theoretical reference for cultivating high quality and high level applied technical talents and thus promoting the optimization and transformation of the talent cultivation mode of universities.

Key words: Education of“specialization and innovation integration”, Application-oriented universities, Talent training, Curriculum system, Higher education, Teaching models