Abstract: Training high-skilled application talents is a systematic project in the era of artificial intelligence, it requires the deep cooperation and joint efforts of teachers and students, enterprises, governments, families and other participants in higher vocational colleges. For this purpose, make clear the goals of higher vocational education and promote the deep integration of artificial intelligence and innovation and entrepreneurship education, construct a complete education system of innovation and entrepreneurship, demand for education, cooperative education, knowledge education, value education,as for some key reality constraints put forward some measures and guarantees for the operation of higher vocational innovation and entrepreneurship education system from the perspective of artificial intelligence.

Key words: Artificial intelligence, Higher vocational innovation and entrepreneurship education, Innovation and entrepreneurship education system