Abstract: Innovation and Entrepreneurship Foundation is a core course that carries innovation and entrepreneurship education through the whole process of talent cultivation. In view of the problems existing in the teaching of the course Innovation and Entrepreneurship Foundation, this paper designs and practices the course based on the online-offline mixed teaching mode of “project leading +task driving”, through the study of the course, students can turn their own entrepreneurial ideas into concrete entrepreneurial actions, and strengthen the cultivation of students' innovative entrepreneurial awareness and practical ability. The curriculum effect is good, the student main body status obtains the remarkable promotion, simultaneously promoted the teacher own teaching accomplishment and the ability enhancement.

Key words: Project leading, Task driving, Mixed teaching mode, Innovation and entrepreneurship