Abstract: Carrying out innovation and entrepreneurship education based on professionalism is an important starting point for the comprehensive reform of innovation and entrepreneurship education in colleges and universities. In recent years, the integration of innovation and entrepreneurship education and professional education has become the focus and difficulty of innovation and entrepreneurship education career in colleges and universities. Starting from the competency model, Northeastern University clarified the relationship between innovation and entrepreneurship education and professional education, analyzed the main reason for the departure of innovation and entrepreneurship education from professional education from the historical background, and under the framework system of ability cultivation, explored the effective path of integration of innovation and entrepreneurship education and professional education from the four dimensions of concept, curriculum, teachers and practice, so as to comprehensively improve the quality of talent cultivation in higher education.

Key words: Ability cultivation of college students, Innovation and entrepreneurship education, Professional education