Abstract: In the face of the continuous promotion and implementation of the current education informatization in college education and teaching, more and more college teachers in the process of curriculum teaching, through the help of network information technology and new teaching media, to achieve the innovation of teaching mode and teaching path. Especially for the teaching of statistics course, there is a certain theoretical and practical nature in the process of promoting the whole course. If some students can't grasp and learn the basic theoretical knowledge well, they can't improve their skills and literacy in the course of statistics. In order to effectively achieve the teaching objectives of statistics course, we should pay attention to the innovation and optimization of hybrid learning mode in the process of learning. Therefore, under the background of the new round of curriculum teaching reform, this paper analyzes and discusses the innovation strategy of Statistics Teaching Mode under the background of online and offline hybrid learning, hoping to provide relevant reference experience for further improving students' ability to apply statistical professional knowledge and discipline core literacy.

Key words: Statistics course, Online and offline, Blended learning, Innovative mode