Abstract: The in-depth integration of clinical practice and basic research is a key approach to advancing medical innovation and improving the level of diagnosis and treatment. This paper focuses on the construction of an experimental teaching center integrating clinical practice and basic research, exploring a collaborative teaching model involving clinicians and basic researchers to achieve the closed-loop training goal of“transforming clinical problems into research projects - basic research solving core mechanisms - research outcomes returning to clinical application”. It constructs a framework for building such an integrated experimental teaching center from the perspectives of platform positioning, hardware layout, teaching system, collaboration mechanism, and effectiveness evaluation, providing practical insights for cultivating interdisciplinary talents with clinical research transformation capabilities and promoting the coordinated development of medical teaching and research.

Key words: Clinical practice, Basic research, Integrated experimental teaching center, Collaborative teaching, Interdisciplinary talents, Coordinated development