Abstract: Biochemistry is a subject that reveals the essence of life phenomena of organisms by chemical language. The teaching of biochemistry involves the theoretical intersection of biology, chemistry, molecular biology and other disciplines. The abstract theory, complex content and huge system of biochemistry often makes it difficult for teachers to teach and students to learn. In the teaching process, the integration of theory with practice can effectively arouse the students' interest to actively learn. Teachers should learn to use obscure basic theoretical knowledge to explain scientific phenomena or practical problems often encountered in real life, so that students can take the initiative to enter the biochemistry class with great interest. Taking the section of the relationship between molecular structure and function of protein as an example, the author discusses the specific design and practice of the teaching method of integration of theory with practice in this section, aiming to provide reference for the teaching reform of biochemistry.

Key words: Biochemistry, Integrate theory with practice, Protein structure, Teaching design