Abstract: Under the background of "new medicine", medical development in border minority nationality regions urgently needs new medical talents with "five skills". Medical cell biology is the basic core course of medical education, and it is imperative to promote the construction of a "golden course" incorporating the concept of "five skills" medical personnel training. Using "receptor-mediated endocytosis" as an example, the instructional design based on student-centered learning concept. We integrated innovative elements such as content reconstruction, curriculum ideological education, digital teaching, interactive simulation experiments and project-based learning into this blended teaching design and practice.

Key words: “New medicine”, Medical talents with “five skills”, Medical cell biology, Student-centered learning