Abstract: The value of innovation and entrepreneurship is increasingly prominent in social and economic development. As the main force of innovation and entrepreneurship education, colleges and universities should rely on market development and market-oriented as the main line to build a multi-level, advanced, and three-dimensional innovation and entrepreneurship practice teaching system to improve the teaching system, teaching practice platform, and curriculum system as a carrier, centering on the content of practical teaching, with the goal of cultivating innovative talents, exploring the practical path of the construction of innovative and entrepreneurial practical teaching system.

Key words: Universities, Multi-level, advanced and three-dimensional, Innovation and entrepreneurship, Practical teaching system