Abstract: Case teaching plays a positive role in promoting innovation and entrepreneurship education. However, in the innovation and entrepreneurship education of Open University, there are problems such as backward ideas, insufficient teachers and lack of cases to reflect the real entrepreneurial situation of open education students.The Marketing major of Guangdong Open University has carried out the reform of entrepreneurship case teaching mode based on social constructivism learning theory, actively carried out the teacher training of innovation and entrepreneurship education, and redefined the relationship in the process of entrepreneurship case teaching. The teachers and students have jointly developed and applied entrepreneurship cases, which achieved good teaching results.

Key words: Open University, Innovation and entrepreneurship education, Case teaching, Social constructivism learning theory