Abstract: As higher vocational colleges pay more and more attention to innovation and entrepreneurship education, higher vocational colleges have gradually formed their own training mode of innovation and entrepreneurship talents. However, in the preliminary investigation, the research group found that there are still a series of outstanding problems to be solved, such as vague understanding of the objectives of innovation and entrepreneurship education in higher vocational colleges and failure to effectively cultivate innovation and entrepreneurship talents. The research group creatively put forward "one center, three integration and one evaluation", that is: " focus on the difficult of enterprises; integrate the needs of students, schools and enterprises; implement a two-way and four-dimensional innovation and entrepreneurship education evaluation system". This implementation path has been implemented in more than 30 higher vocational colleges in China and has been highly praised by schools, students, enterprises and domestic well-known experts.

Key words: Industrial difficulties, Higher vocational colleges, Innovation and entrepreneurship education, Integration of industry and education, Reform in education, Personnel training