Abstract: The innovation and entrepreneurship education of the chemical industry in higher vocational colleges must combine the characteristics of the chemical industry and the development needs of the chemical industry, correctly position the goal of the innovation and entrepreneurship education of the chemical industry, strengthen the construction of teachers, optimize the talent training plan, and actively promote the "Double main body education". In Nanjing Polytechnic Institute, for example, the school in exploring practice, actively build set innovation consciousness training, entrepreneurial quality training and innovation entrepreneurship curriculum system, constantly optimize its characteristics of chemical professional innovation entrepreneurship "four guarantee" education mechanism, the innovation education throughout the whole process of talent training, improve the level of innovation education, let students in innovation entrepreneurship learning and practice to enhance consciousness, exercise ability, improve quality.

Key words: Higher vocational colleges, Chemical engineering majors, Innovation and entrepreneurship education, Curriculum system, Education mechanism