Abstract: Based on the background of "double first-class" construction in colleges and universities, this paper analyzes why university laboratories should carry out innovation and entrepreneurship education reform and puts forward the strategies for university laboratories to adapt to innovation and entrepreneurship education. First of all, it is necessary to establish a sustainable development mechanism, optimize the teaching staff, and manage the laboratory scientifically. Then, it is necessary to reorganize the experimental courses, innovate the teaching means, increase the opening of the laboratory, and realize the sharing of experimental resources. Finally, it is necessary to strengthen the experimental communication between schools and enterprises, focusing on innovation and entrepreneurship projects and major events, and strengthening the culture construction of laboratory innovation and entrepreneurship.

Key words: University laboratory, Innovation and entrepreneurship, Education reform