Abstract: Deepening the reform of innovation and entrepreneurship education has become a strategic task for the reform and development of colleges and universities in China. Integrating innovation and entrepreneurship education into the teaching of professional courses is of great significance to the cultivation of high-quality application-oriented undergraduates who meet the needs of society. Food microbiology course is a professional course of food and biological engineering. In this paper, the teaching reform of the course under the background of innovation and entrepreneurship is discussed from the aspects of teaching content, teaching methods, evaluation methods and so on, in order to improve the teaching quality and cultivate high-quality talents with innovative thinking, innovation and entrepreneurship ability for the society and food industry.

Key words: Food microorganism, Innovation and entrepreneurship, Teaching reform, The combination of production, learning, research and innovation