Abstract: As a highly fusion of higher education and informatization, MOOC-based mixed teaching has become a new direction of college teaching reform. Therefore, it is of great pedagogical significance to construct high-quality online courses with the characteristics of our school and explore the application effects of blended teaching reforms based on this. In our school, the biochemistry course is a required examination course for undergraduate clinical and nursing students. It is one of the core courses of basic medicine and will initially implement mixed teaching in 2019. This article aims to analyze the current courses of the MOOC platform, the construction of the characteristic resources of Sanquan College and its application effects, and provide support and guarantee for the continued development of mixed teaching reforms.

Key words: MOOC, Biochemistry, Teaching reform