Abstract: The emergence of MOOC plays an important role in promoting the deepening reform of innovation and entrepreneurship education. Outstanding MOOCS are constantly introduced into innovation and entrepreneurship education, which improves the quality of innovation and entrepreneurship education in vocational colleges. At the same time, a large number of advanced vocational schools start to think about the online and offline blended teaching mode and constantly explore the construction of the online and offline blended teaching mode in our school. Being the first batch of demonstration schools for innovation and entrepreneurship in Guangdong province, Guangdong Business and Technology University has been exploring innovation and entrepreneurship education and teaching, constructing the online and offline blended teaching mode from the following aspects: the establishment of teaching objectives, the reform of teaching contents, the design of teaching activities and the evaluation of teaching.After several rounds of teaching practice, good teaching results have been obtained.

Key words: Advanced vocational school, Innovation and entrepreneurship, Blended, Optimization of teaching mode