Abstract: When deepening the reform of innovation and entrepreneurship education has become an important mission of China's undergraduate colleges and universities, curriculum-based system and the school-enterprise collaborative education can become an important focus of undergraduate colleges and universities to promote innovation and entrepreneurship education reform. Compared with the traditional credit system and elective system, the curriculum-based system has obvious advantages. at present, there are three bottlenecks in the innovation and entrepreneurship education of undergraduate colleges and universities, such as monotonous curriculum design, lack of teaching staff and virtual entrepreneurship practice.Promoting the "three integration" based on school-enterprise collaborative education and curriculum-based system,integrating the innovation and entrepreneurship program into the program of cultivating talents,and solving the course design,course teaching and practice platform by the deep integration of the school and enterprise can effectively eradicate these three bottlenecks,and deepen the innovation and entrepreneurship education reform of undergraduate colleges and universities.

Key words: Curriculum-based system, School-enterprise collaborative education, Innovation and entrepreneurship education, Talent cultivating