Abstract: The digital transformation of higher education is the direct embodiment of digital China in the field of education, and also an important driving force to achieve educational equity and high-quality development. The application of generative AI technology to college education not only realizes the intelligent interaction between teachers and students, but also achieves the effect of optimizing teaching business decision-making and constructing intelligent education paradigm. With the deep integration of generative AI and college education, the overall transformation of teaching subject to multi-role, teaching content to open, and teaching method to diversified will be realized. In order to better play the role of generative AI in enabling the digital transformation of college education, suggestions are put forward to improve the digital teaching infrastructure, improve teachers'digital literacy and AI literacy, strengthen data security management, and build a human-machine collaborative teaching digital ecosystem.

Key words: Generative AI, Higher education, Digitization, Man-machine coordination, Data security, Personnel training