Abstract: The talent cultivation in digital economy programs at application-oriented universities faces the challenge of disconnection between traditional educational models and industrial demands, urgently requiring the establishment of a distinctive integration system that combines professional education with innovation and entrepreneurship. The“learning-innovation integration”model achieves deep integration of professional education and innovation-entrepreneurship education by constructing a three-dimensional cultivation framework powered by digital technology, driven by industrial projects, and supported by university-enterprise collaborative education, thereby forming an integrated educational mechanism that simultaneously advances professional learning and innovation-entrepreneurship. This distinctive model reshapes the curriculum system of digital economy programs, innovates project-based teaching approaches, establishes multi-stakeholder collaborative practice platforms, and implements comprehensive operational mechanisms and quality assurance systems. The model constructs dynamic operational mechanisms, multi-dimensional evaluation systems, and continuous improvement mechanisms, providing application-oriented universities with a sustainable and innovative paradigm for cultivating interdisciplinary talents in the digital economy field.

Key words: "Learning-innovation integration", Integration of professional education and innovation-entrepreneurship, Digital economy programs, Application-oriented universities, Distinctive model, Talent cultivation