Abstract: Under the national upsurge of “mass entrepreneurship and innovation”, scientific and technological innovation activities have become a key project of undergraduate education. Therefore, the cultivation of college students' innovative and entrepreneurial ability is an inevitable option in the current undergraduate talent training process.This article mainly takes the maker-education and its own unique charm as the innovative entrepreneurship education concept to cultivate students' innovative thinking, innovative methods, innovative consciousness and innovative ability. Based on the training of innovative talents in the secondary faculties of colleges and universities, we are in the process of cultivating the majority of students, constructing a systematic teaching model for innovative entrepreneurship education, implementing a "four-stage" practical ability training model for innovative entrepreneurship, carrying out multi-level three-dimensional technology innovative practice activities and other paths, creating college and university students' innovation and entrepreneurship ability training system construction in the scientific and technological innovation activities, and it begins with the establishment and successful implementation of the Department of Innovation and Entrepreneurship of secondary students ("Double Innovation Department") as the starting point, it has formed a wave of active use of what they have learned among the majority of undergraduates.

Key words: Scientific and technological innovation, Maker, Innovation ability, Innovation consciousness, "Four-stage" training system.