Abstract: From the perspective of collaborative education, this paper analyzes the problems existing in the cultivation of innovative and entrepreneurial ability of contemporary college students, with the goal of improving the innovative and entrepreneurial ability of college students, establishes a multi-agent collaborative training management system and working mechanism, constructs a“2+3+4+5+6”two-class multi-agent collaborative training mode, innovates collaborative training programs and curriculum systems, creates a diversified collaborative training platform, and optimizes collaborative training incentives and evaluation methods, create a good cultural atmosphere for innovation and entrepreneurship education, provide theoretical support for collaborative cultivation of innovation and entrepreneurship ability, and further promote the development of collaborative cultivation of innovation and entrepreneurship ability of college students.

Key words: College students, Innovation and entrepreneurship ability, Two classes, Collaborative cultivation, Collaborative education, Integration of industry and education