Abstract: The rapid development of the Internet and intelligent 5G equipment, which has contributed to the development and continuous improvement and innovation of online teaching mode. As a result, micro-lessons with micro teaching videos as the carrier, personalized teaching and fragmentary memory as the concept and supported by the Internet platform become the focus in the teaching reform of the connotative development of medical higher education. At the same time, as a basic medical course-pathology, the traditional experimental teaching has been unable to meet the development needs of current medical higher education. Based on this research, the experimental teaching reform of pathology is carried out. Discuss the significance of micro-lessons in the experimental course of pathology, and record micro-lessons, the flipped classroom design based on the micro-lesson, the case discussion, and the construction of after-school resources based on the micro-course platform are carried out, as well as the construction of after-school resources based on the micro-lesson App, etc, and conduct course formative evaluation and after-class questionnaire survey to evaluate the teaching effect. Through the thinking, exploration and attempt of the pathology experimental course, the students' independent learning ability has been significantly improved, and the initial effect of "overall thinking of disease" and the obvious enhancement of the ability to innovate and practice has been preliminarily realized, which provides a reference for the teaching reform of the pathology experimental course.

Key words: Micro-course, Pathology, Experimental course, Teaching reform, Teaching effect, High quality courses