Abstract: Proceeding from the social needs, in view of the practical problems existing in higher education, such as the low recognition of students' learning process, the low dominant position, the unbalanced development of classroom teaching and practice education, and the lack of focus on interdisciplinary knowledge integration, based on the project-based and practical characteristics of PBL theory, we designed and implemented the curriculum reform of "one game, one lesson, and integration of teaching and competition", and implemented the curriculum, project, competition, the construction of innovation and entrepreneurship curriculum group connected with the base expands the practical education approach of innovation and entrepreneurship education, so as to expand the coverage of innovation and entrepreneurship education, expand the education dimension, enhance the sense of gain and happiness of teachers and students, and constantly improve the education level and practical effect of innovation and entrepreneurship education.

Key words: PBL theory, Innovation and entrepreneurship, "Integration of teaching and competition", "One game, one lesson", Project-based learning, Curriculum reform