Abstract: In the process of implementing innovation and entrepreneurship education, application-oriented universities need to integrate the talent training system of professional education into the framework of innovation and entrepreneurship education system. Based on applied undergraduate colleges and universities of innovation entrepreneurship education as the main research direction, from the perspective of cultivating the ability of students' comprehensive applied undergraduate colleges, analyzed the "professional education and the integration of innovative entrepreneurship education" of value and the new era of innovation entrepreneurship education talent cultivation system frame structure, and shift from education concept and teaching model reform perspective, further explore the specific practice path of integrating innovation and entrepreneurship education into professional education. In the process of innovation and entrepreneurship education, colleges and universities innovatively integrate professional education and school-enterprise cooperation into the teaching system, which can effectively improve the social adaptability and innovation and entrepreneurship ability of college students.

Key words: Core literacy, Innovation and entrepreneurship education, Teaching method reform, Social adaptability, Professional education, Education concept