Practice and Exploration of Improving Scientific Research and Clinical Ability of Medical Undergraduates Based on Animal Disease Model Construction

Abstract

Abstract: The objective of the study was to analyze and evaluate the application effect of improving scientific research and clinical ability of medical undergraduates based on animal disease model construction. A rat model of cavernous nerve injury related erectile dysfunction was established by medical undergraduates in the early stage to evaluate its influence on the students' scientific research and clinical ability. At the same time, a questionnaire survey was conducted to evaluate students' satisfaction with the teaching model. After the construction of animal disease model, the students' scientific research ability was significantly improved (28.69±2.46 vs 22.38±3.37, P < 0.01). Also, the clinical ability of surgical hand washing (8.12±1.07 vs 5.81±0.75, P < 0.01), suture and knotting (45.38±5.66 vs 36.96±4.60, P < 0.01) were significantly improved, respectively. The satisfaction survey shows that most students believe the teaching mode can effectively improve their scientific research and clinical level. The animal disease model training can effectively improve the scientific research and clinical ability of medical undergraduates, and has been recognized by the students.

Key words: Animal model, Medical undergraduate, Surgical teaching, Scientific research, Clinic, Cavernous nerve

CLC Number:

G642

MENG Xianghu, CONG Rong, YAO Liangyu, YE Jun, HUANG Huaxing, SONG Rijin. Practice and Exploration of Improving Scientific Research and Clinical Ability of Medical Undergraduates Based on Animal Disease Model Construction[J]. The Theory and Practice of Innovation and Enntrepreneurship, 2022, 5(24): 166-169.

References

[1] Rong Cong,Yi Wang,Yamin Wang,et al.Comprehensive analysis of lncrna expression pattern and lncrna-mirna-mrna network in a rat model with cavernous nerve injury erectile dysfunction[J].J Sex Med, 2020,17(9): 1603-1617.
[2] Raterman E L, Jerse A E.Female mouse model of neisseria gonorrhoeae infection[J].Methods Mol Biol,2019:413-429.
[3] Yingying Pan,Mingzhu Cao,Danming You,et al.Research progress on the animal models of drug-induced liver injury: current status and further perspectives[J].BioMed Research International,2019:1283824.
[4] Gaikwad S, Birla S, Ingle AP, et al.Superior in vivo Wound-Healing Activity of Mycosynthesized Silver Nanogel on Different Wound Models in Rat[J]. Front Microbiol, 2022, 13:881404.
[5] 钟奇祺,张海波,黎力之,等.肠道分节丝状菌对宿主肠黏膜免疫系统的影响及其在模式动物中的研究进展[J].中国畜牧杂志,2021,57(5):17-22.
[6] 朱医高,李军,逄越,等.七鳃鳗:生物进化和疾病研究的重要模式动物[J].遗传,2020,42(9):847-857.
[7] 梁向艳,赵妍妍,吴金玉,等.课外科研中医学本科生开展动物实验的探讨[J].西部素质教育, 2019,5(11):209-210.
[8] 朱国斌,袁海泉,郑洪河.本科生科研训练型实验评价研究[J].实验室科学,2017,20(5):233-237.
[9] Wang yi, Meng Xianghu,Zhang Qijie,et al.Losartan improves erectile function through suppression of corporal apoptosis and oxidative stress in rats with cavernous nerve injury.[J].Asian J Androl, 2019,21(5): 452-459.
[10] 谭斯品,肖子辉,涂自智,等.研究生课程“人类疾病动物模型的研究进展”的设立与实践[J].高校医学教学研究(电子版),2019,9(4):39-43.
[11] 王宏刚,陈成彬,王春国,等.本科生开设“动物细胞培养”实验的探索[J].实验室研究与探索,2014,33(6):165-168,242.
[12] 陈思怀,高继业,唐发书.在普通实验室开展本科生动物细胞培养教学实验的设想[J].安徽农业科学,2018,46(9):220-221.
[13] 王亚民,高翔,王巍,等.床边教学在临床医学本科生见习与实习中的困局分析及对策[J].南京医科大学学报(社会科学版),2021,21(4):409-412.
[14] 孟祥虎,丛戎,宋日进,等.基于SPOC医学论文写作的教学研究[J].卫生职业教育,2020,38(2):21-22.
[15] 丛登立,赵丽纯.利用翻转课堂提高医药专业本科生实验动物技能操作的探索[J].中国实验诊断学,2020,24(8):1404-1407.