Abstract: To solve the problems of insufficient teaching resources and single teaching modes in the teaching of pharmaceutical science and technology paper writing courses in higher vocational education, this article carries out teaching reforms on pharmaceutical science and technology paper writing courses from the aspects of teacher team building, revising curriculum standards, reconstructing teaching content, developing online teaching resources, organizing online and offline teaching activities, and reforming course assessment and evaluation. Practical results have shown that the blended learning mode of online and offline has enriched teaching resources, enhanced students'self-learning ability, better met their diverse learning needs, improved the quality of course teaching, and provided useful references for the reform of pharmaceutical science and technology paper writing course teaching.

Key words: Vocational education, Pharmaceutical technology paper writing, Course, Online and offline hybrid, Reform in teaching, Practice