Abstract: Medical education cooperation refers to the close coordination between schools and hospitals, and the joint participation in the cultivation of medical talents. Innovation and entrepreneurship education aims to cultivate talents with Entrepreneurship basic quality and pioneering personality, not only to cultivate the entrepreneurship consciousness, innovation spirit and innovation and entrepreneurship ability of school students, but also to face the whole society, aiming at those who plan to start a business and have already started a business The successful entrepreneurial groups should carry out the education of innovative thinking and entrepreneurial ability training by stages and levels. For medical students, integrating the cultivation of innovative thinking into the collaborative education mode of medical education can truly combine the school's innovation and entrepreneurship education with professional education, and make the innovation and entrepreneurship education come into being.

Key words: Medical education collaborative, Innovation thinking, Innovation entrepreneurship education